![]() It is likely through these channels that DIM has a hormone-balancing effect on the body, no matter your sex. Īll of this really boils down to DIM supporting healthier hormone ratios in men and women. DIM suppresses the ability of aromatase to convert testosterone to estradiol, thereby increasing the availability of free testosterone in men. The overall effect is an increase in estrogenic influence. ![]() As men age, their levels of testosterone naturally decline, while the activity of the enzyme that converts testosterone into estrogen, called “aromatase”, increases. Most male estrogen is made by the conversion of the androgenic hormone, testosterone, to estradiol. DIM has been shown to reduce estrogen receptor activity, promote healthy estrogen metabolite production, and support selective apoptosis, which helps to get rid of damaged cells from the body. The estrogen metabolites produced through DIM pathways are known as 2-OH estrogens and have a severely less-pronounced estrogenic effect than the 16-OH estrogens and 4-OH estrogens. Some estrogens, such as those more commonly associated with breast cancer, can cause inflammation, uncontrolled cellular mutation, and over-proliferation of cells. It should be noted, however, that there are different types of estrogen. Since then, research has shown that estrogen is utilized by every organ in the body, in humans of all genders. Up until the 1990s, it was commonly believed that estrogen was just a female hormone, and played little to no role in male hormonal balance. Whether you are male or female, DIM may help to balance your hormones.ĭIM is a regulator of estrogen metabolism, as it promotes both breakdown and synthesis of estrogen in the body. Please read on to learn about different ways in which adding DIM to your supplemental regimen may support your overall health. Your skin, however, is not the only part of the body that benefits from the action of this natural compound. ![]() Below, we offer some scientific background info on how DIM works in your body, to better understand how DIM may support clear, healthy skin. Recently, DIM has received a lot of positive attention in health publications for its benefits in the healing of hormonal acne. This is why supplementation is so beneficial. In order to get the recommended daily amount of DIM however, one would have to eat more than two pounds of these vegetables a day. It is a naturally occurring substance generated when acids in the stomach break down indole-3-carbinol (I3C), a compound found in cruciferous vegetables such as kale, broccoli, cabbage, and brussels sprouts. What is DIM and how does it work with hormones? Diindolylmethane (or DIM) is both an antioxidant and phytonutrient.
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